PhD Student (m/f/d) in the field of Cancer Epigenetics
Sabine Taschner-Mandl Group
To strengthen our excellent research team, which is focused on the development and research of innovative approaches for the treatment of childhood cancer, we are looking for a PhD Student (m/f/d) in the field of Cancer Epigenetics. In this responsible role, you will have the unique opportunity to be part of a multidisciplinary competence center for pediatric oncology and to have a direct influence on the development of new cancer therapies.
The Taschner-Mandl group tackles unresolved questions of neuroblastoma pathogenesis and develops new diagnostic and therapeutic approaches to facilitate precision medicine for children with malignant tumors. In this project, we will study determinants of inter- and intra-tumor heterogeneity and metastasis in neuroblastoma from an epigenetics perspective (e.g., Weiss T et al., Nat Comm 2021, Fetahu et al. Sci Adv 2019, Wu et al., Nature 2018). This project, will employ an array of state-of-the art technical approaches, including single-cell (sc)ATAC-seq, scRNA-seq, CRISPR/Cas9, TAP, and SILAC.
As a PhD student, you will
Join an exciting, multi-disciplinary environment with a strong support for your personal and professional development from your supervisor, team, and peers
Be part of an interdisciplinary research project on deciphering the epigenetic determinants that underlie the neuroblastoma pathology and their role as potential biomarkers in the diagnosis of the disease
Learn to take on ambitious research in close collaboration with experimental and clinical researchers
You will contribute from the start, including planning of experiments and data acquisition
You will provide thorough and creative thinking that makes these projects a success
Monitor the literature and community resources to keep abreast latest developments and to identify information, data, and methods to integrate in your own work
Write papers, present your research at conferences, apply for fellowships, and contribute to grants
Master’s degree in a relevant subject (biology, molecular biology, or similar)
Laboratory experience, especially in the epigenetic-related technologies is preferred
Motivation to pursue an ambitious research agenda
Excellent verbal and written communication skills in English (German not required)
Self-motivated, enthusiastic, and eager to learn
Good team player, commitment, and creative
Scientific mindset, problem solving attitude
A meaningful, inspiring, and international environment
An outstanding working atmosphere in a strong team with excellent research and development opportunities
Access to state-of-the-art infrastructure
Flexible working hours, discounted lunch and other great benefits
Great location in the center of Vienna, a capital of biomedical research in Europe with excellent quality of life
The St. Anna Children’s Cancer Research Institute (CCRI), located in the center of Vienna, the world’s most livable city and one of Europe’s most important places for biomedical research and life sciences, is an international and multidisciplinary competence center striving to improve treatment of children and adolescents with cancer by connecting translational and clinical research with open-minded exploration of basic disease mechanisms. Through close cooperation between clinic and research, the CCRI provides an ideal environment for cutting-edge research and its translation into clinical practice. To achieve our ultimate goal of advancing the well-being of patients, the CCRI constantly pushes scientific boundaries and strongly promotes close collaboration and exchange with external institutions like the Medical University of Vienna, CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, the Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA) and the Institute of Molecular Pathology (IMP).
The CCRI is an equal opportunity employer. We value diversity and are committed to providing a work environment of mutual respect to everyone without regard to ethnicity, religion, national origin, age, gender identity or expression, disability, or any other characteristic protected by applicable laws, regulations and ordinances.
We are looking forward to your application! Applications should at least contain your Curriculum Vitae, a cover letter, list of publications (please mark / explain your three top contributions), and the contact details of three references.